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医学院药学导师介绍:
程雅红,女,博士,电子邮箱:774300747@qq.com,
电话:18627009067
毕业院校:武汉大学药学院;专业:神经药理学。
研究方向:
1. 情绪和食品添加剂介导的糖脂代谢变化对脑神经生理病理影响研究;
2. 短链脂肪酸和膳食纤维对小鼠脑部能量代谢的影响研究;
3. 以能量代谢为靶点的癫痫发病机制及创新药物筛选研究;
4. 靶向线粒体的抗癫痫药物筛选及机制研究。
科研经历
1. 国家自然科学基金青年项目,糖酵解/H3K18la/TRIM24正反馈环路介导癫痫后线粒体能量代谢障碍及丙酸钙干预研究(82301650),2024.01-2026.12,主持在研;
2. 湖北省科学技术厅,湖北省技术创新专项(重大项目),220171403,类糖皮质激素药物在新型冠状病毒肺炎中的临床应用,2020-03至2022-06,参与;
3. 博士科研启动经费,基于PINK1/Parkin调控神经元线粒体自噬探讨杨梅素防治癫痫的药效机制研究(2023RZ037),2023.01-2025.12,主持。
发表文章
[1] Cheng Y, Zeng X, Mai Q, Bai X, Jiang Y, Li J, Fan S, Ding H. Insulin injections inhibits PTZ-induced mitochondrial dysfunction, oxidative stress and neurological deficits via the SIRT1/PGC-1α/SIRT3 pathway[J]. Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2021, 1867(6): 166124.
[2] Li J, Zhang Y, Zeng X, Cheng Y, Tang L, Hong D, Yang X. Lycopene ameliorates insulin resistance and increases muscle capillary density in aging via activation of SIRT1[J]. The Journal of Nutritional Biochemistry, 2022, 99: 108862.
[3]Nicotinamide mononucleotide alleviates seizures via modulating SIRT1-PGC-1α mediated mitochondrial fusion and fission. Journal of Neurochemistry. 2024
[4]Luteolin ameliorates pentetrazole-induced seizures through the inhibition of the TLR4/NF-κB signaling pathway. Epilepsy Research. 2024
[5]Propionate ameliorates diabetes-induced neurological dysfunction through regulating the PI3K/Akt/eNOS signaling pathway. European Journal of Pharmacology. 2022
[6]Ferric citrate for the treatment of hyperphosphatemia and iron deficiency anemia in patients with NDD-CKD: A systematic review and meta analysis. 3rd International Conference on
Biological Engineering and Medical Science (ICBioMed 2023). 2023